AIMC Topic: Galantamine
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A pendant droplet-based sensor for the detection of acetylcholinesterase and its inhibitors.
Chemical communications (Cambridge, England)
Sep 6, 2021
In this work, a pendant droplet-based sensor is developed for the rapid and label-free detection of acetylcholinesterase (AChE) and its inhibitors. The detection limit of AChE reaches 0.17 mU mL. The pIC values of AChE inhibitors such as neostigmine,...
Design of Natural-Product-Inspired Multitarget Ligands by Machine Learning.
ChemMedChem
May 16, 2019
A virtual screening protocol based on machine learning models was used to identify mimetics of the natural product (-)-galantamine. This fully automated approach identified eight compounds with bioactivities on at least one of the macromolecular targ...
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