AIMC Topic: Granulocyte-Macrophage Colony-Stimulating Factor
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Concentration-dependent effects of immunomodulatory cocktails on the generation of leukemia-derived dendritic cells, DC mediated T-cell activation and on-target/off-tumor toxicity.
Frontiers in immunology
Jan 30, 2025
Acute myeloid leukemia (AML) remains a devastating diagnosis in clear need of therapeutic advances. Both targeted dendritic cells (DC) and particularly leukemia-derived dendritic cells (DC) can exert potent anti-leukemic activity. By converting AML b...
Prediction of six macrophage phenotypes and their IL-10 content based on single-cell morphology using artificial intelligence.
Frontiers in immunology
Jan 4, 2024
INTRODUCTION: The last decade has led to rapid developments and increased usage of computational tools at the single-cell level. However, our knowledge remains limited in how extracellular cues alter quantitative macrophage morphology and how such mo...
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