AIMC Topic: Immunogenicity, Vaccine

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and cell-based analyses reveal strong divergence between prediction and observation of T-cell-recognized tumor antigen T-cell epitopes.

The Journal of biological chemistry May 23, 2017
Tumor exomes provide comprehensive information on mutated, overexpressed genes and aberrant splicing, which can be exploited for personalized cancer immunotherapy. Of particular interest are mutated tumor antigen T-cell epitopes, because neoepitope-s...
Humans Artificial Intelligence Cells, Cultured Melanoma Reproducibility of Results Animals Computational Biology Cancer Vaccines Antigens, Neoplasm Vaccines, Synthetic Membrane Proteins Neoplasm Proteins Mice, Knockout Peptide Fragments Epitopes HLA-A2 Antigen Protein Stability Expert Systems Oligopeptides Immunogenicity, Vaccine Mice, Transgenic Models, Immunological Protein Refolding T-Lymphocytes, Cytotoxic
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