AIMC Topic: Leigh Disease
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Quantifying small molecule phenotypic effects using mitochondrial morpho-functional fingerprinting and machine learning.
Scientific reports
Jan 26, 2015
In primary fibroblasts from Leigh Syndrome (LS) patients, isolated mitochondrial complex I deficiency is associated with increased reactive oxygen species levels and mitochondrial morpho-functional changes. Empirical evidence suggests these aberratio...
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