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Lubricant Eye Drops

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Preparation, characterization and biocompatibility studies of thermoresponsive eyedrops based on the combination of nanostructured lipid carriers (NLC) and the polymer Pluronic F-127 for controlled delivery of ibuprofen.

Pharmaceutical development and technology 28240141
CONTEXT: Nanostructured lipid carrier (NLC) dispersions present low viscosity and poor mucoadhesive properties, which reduce the pre-corneal residence time and consequently, the bioavailability of ocular drugs.
Anti-Inflammatory Agents, Non-Steroidal Cell Line, Tumor Cell Survival Delayed-Action Preparations Drug Carriers Drug Compounding Drug Liberation Drug Stability Humans Ibuprofen Lipids Lubricant Eye Drops Nanostructures Ophthalmic Solutions Poloxamer Rheology Surface Properties Viscosity
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