AIMC Topic: Machine Learning

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A convolutional neural network based tool for predicting protein AMPylation sites from binary profile representation.

Scientific reports
AMPylation is an emerging post-translational modification that occurs on the hydroxyl group of threonine, serine, or tyrosine via a phosphodiester bond. AMPylators catalyze this process as covalent attachment of adenosine monophosphate to the amino a...

Visible Particle Identification Using Raman Spectroscopy and Machine Learning.

AAPS PharmSciTech
Visible particle identification is a crucial prerequisite step for process improvement and control during the manufacturing of injectable biotherapeutic drug products. Raman spectroscopy is a technology with several advantages for particle identifica...

Dynamically Weighted Balanced Loss: Class Imbalanced Learning and Confidence Calibration of Deep Neural Networks.

IEEE transactions on neural networks and learning systems
Imbalanced class distribution is an inherent problem in many real-world classification tasks where the minority class is the class of interest. Many conventional statistical and machine learning classification algorithms are subject to frequency bias...

A structural characterization of shortcut features for prediction.

European journal of epidemiology
With the rising use of machine learning for healthcare applications, practitioners are increasingly confronted with the limitations of prediction models that are trained in one setting but meant to be deployed in several others. One recently identifi...

Breast Cancer Detection on Histopathological Images Using a Composite Dilated Backbone Network.

Computational intelligence and neuroscience
Breast cancer is a lethal illness that has a high mortality rate. In treatment, the accuracy of diagnosis is crucial. Machine learning and deep learning may be beneficial to doctors. The proposed backbone network is critical for the present performan...

Machine learning-enabled resolution-lossless tomography for composite structures with a restricted sensing capability.

Ultrasonics
Construction of a precise ultrasound tomographic image is guaranteed only when the sensor network for signal acquisition is of adequate density. On the other hand, machine learning (ML), as represented by artificial neural network and convolutional n...

Machine learning for improving high-dimensional proxy confounder adjustment in healthcare database studies: An overview of the current literature.

Pharmacoepidemiology and drug safety
PURPOSE: Supplementing investigator-specified variables with large numbers of empirically identified features that collectively serve as 'proxies' for unspecified or unmeasured factors can often improve confounding control in studies utilizing admini...

Prediction of postoperative cardiac events in multiple surgical cohorts using a multimodal and integrative decision support system.

Scientific reports
Postoperative patients are at risk of life-threatening complications such as hemodynamic decompensation or arrhythmia. Automated detection of patients with such risks via a real-time clinical decision support system may provide opportunities for earl...

Mediation analysis using Bayesian tree ensembles.

Psychological methods
We present a general framework for causal mediation analysis using nonparametric Bayesian methods in the potential outcomes framework. Our model, which we refer to as the Bayesian causal mediation forests model, combines recent advances in Bayesian m...