Benkeser et al. demonstrate how adjustment for baseline covariates in randomized trials can meaningfully improve precision for a variety of outcome types. Their findings build on a long history, starting in 1932 with R.A. Fisher and including more re...
Studies in health technology and informatics
Jan 25, 2024
Clinical data de-identification offers patient data privacy protection and eases reuse of clinical data. As an open-source solution to de-identify unstructured clinical text with high accuracy, CliniDeID applies an ensemble method combining deep and ...
Studies in health technology and informatics
Jan 25, 2024
Dengue fever is a viral infectious disease transmitted through mosquito bites, and has symptoms ranging from mild flu-like symptoms to deadly complications. Dengue fever is one of the global burden diseases which annually have 50-100 million cases wi...
Studies in health technology and informatics
Jan 25, 2024
The lack of transparency and explainability hinders the clinical adoption of Machine learning (ML) algorithms. While explainable artificial intelligence (XAI) methods have been proposed, little research has focused on the agreement between these meth...
Studies in health technology and informatics
Jan 25, 2024
We have developed a time-oriented machine-learning tool to predict the binary decision of administering a medication and the quantitative decision regarding the specific dose. We evaluated our tool on the MIMIC-IV ICU database, for three common medic...
Studies in health technology and informatics
Jan 25, 2024
Nursing staff record observations about older people under their care in free-text nursing notes. These notes contain older people's care needs, disease symptoms, frequency of symptom occurrence, nursing actions, etc. Therefore, it is vital to develo...
Studies in health technology and informatics
Jan 25, 2024
With growing use of machine learning (ML)-enabled medical devices by clinicians and consumers safety events involving these systems are emerging. Current analysis of safety events heavily relies on retrospective review by experts, which is time consu...
Studies in health technology and informatics
Jan 25, 2024
We document the procedure and performance of a rule-based NLP system that, using transfer learning, automatically extracts essential named entities related to drug errors from Japanese free-text incident reports. Subsequently, we used the rule-based ...
Studies in health technology and informatics
Jan 25, 2024
Real-world performance of machine learning (ML) models is crucial for safely and effectively embedding them into clinical decision support (CDS) systems. We examined evidence about the performance of contemporary ML-based CDS in clinical settings. A ...
Integrative biology : quantitative biosciences from nano to macro
Jan 23, 2024
Combinations of genes or proteins work in synergy at different times and durations in a signaling pathway. However, which combinations are prevalent at a particular time point or duration is mostly not known. Sensitivity analysis plays a major role i...
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