The published biomedical research literature encompasses most of our understanding of how drugs interact with gene products to produce physiological responses (phenotypes). Unfortunately, this information is distributed throughout the unstructured te...
BACKGROUND: It is unclear which terms should be included in bibliographic searches for randomized controlled trials (RCTs) of drugs, and identifying relevant drug terms can be extremely laborious. The aim of our analysis was to determine whether a bi...
IEEE/ACM transactions on computational biology and bioinformatics
Jan 1, 2015
With the rapid development of biomedical sciences, a great number of documents have been published to report new scientific findings and advance the process of knowledge discovery. By the end of 2013, the largest biomedical literature database, MEDLI...
Studies in health technology and informatics
Jan 1, 2015
Dependence relations among disease and risk factors are a key ingredient in risk modeling and decision support models. Currently such information is either provided by experts (costly and time consuming) or extracted from data (if available). The pub...
Studies in health technology and informatics
Jan 1, 2015
We examined a process for automating the classification of articles in MEDLINE aimed at minimising manual effort without sacrificing accuracy. From 22,808 articles pertaining to 19 antidepressants, 1000 were randomly selected and manually labelled ac...
Studies in health technology and informatics
Jan 1, 2015
The massive accumulation of biomedical knowledge is reflected by the growth of the literature database MEDLINE with over 23 million bibliographic records. All records are manually indexed by MeSH descriptors, many of them refined by MeSH subheadings....
Studies in health technology and informatics
Jan 1, 2015
Relation extraction typically involves the extraction of relations between two or more entities occurring within a single or multiple sentences. In this study, we investigated the significance of extracting information from multiple sentences specifi...
Studies in health technology and informatics
Jan 1, 2015
As part of the Open Government Initiative, the United States federal government published datasets to increase collaboration, transparency, consumer participation, and research, and are available online at HealthData.gov. Currently, HealthData.gov do...