AIMC Topic: Microscopy

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Assessing Fuchs Corneal Endothelial Dystrophy Using Artificial Intelligence-Derived Morphometric Parameters From Specular Microscopy Images.

Cornea
PURPOSE: The aim of this study was to evaluate the efficacy of artificial intelligence-derived morphometric parameters in characterizing Fuchs corneal endothelial dystrophy (FECD) from specular microscopy images.

A high-speed microscopy system based on deep learning to detect yeast-like fungi cells in blood.

Bioanalysis
Blood-invasive fungal infections can cause the death of patients, while diagnosis of fungal infections is challenging. A high-speed microscopy detection system was constructed that included a microfluidic system, a microscope connected to a high-sp...

Deep Learning-Based Culture-Free Bacteria Detection in Urine Using Large-Volume Microscopy.

Biosensors
Bacterial infections, increasingly resistant to common antibiotics, pose a global health challenge. Traditional diagnostics often depend on slow cell culturing, leading to empirical treatments that accelerate antibiotic resistance. We present a novel...

CellT-Net: A Composite Transformer Method for 2-D Cell Instance Segmentation.

IEEE journal of biomedical and health informatics
Cell instance segmentation (CIS) via light microscopy and artificial intelligence (AI) is essential to cell and gene therapy-based health care management, which offers the hope of revolutionary health care. An effective CIS method can help clinicians...

Current Landscape of Advanced Imaging Tools for Pathology Diagnostics.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Histopathology relies on century-old workflows of formalin fixation, paraffin embedding, sectioning, and staining tissue specimens on glass slides. Despite being robust, this conventional process is slow, labor-intensive, and limited to providing two...

Protocol to train a support vector machine for the automatic curation of bacterial cell detections in microscopy images.

STAR protocols
Manual curation of bacterial cell detections in microscopy images remains a time-consuming and laborious task. This work offers a comprehensive, step-by-step tutorial on training a support vector machine to autonomously distinguish between good and b...

Phase Aberration Correction for In Vivo Ultrasound Localization Microscopy Using a Spatiotemporal Complex-Valued Neural Network.

IEEE transactions on medical imaging
Ultrasound Localization Microscopy (ULM) can map microvessels at a resolution of a few micrometers ( [Formula: see text]). Transcranial ULM remains challenging in presence of aberrations caused by the skull, which lead to localization errors. Herein,...

A clinical microscopy dataset to develop a deep learning diagnostic test for urinary tract infection.

Scientific data
Urinary tract infection (UTI) is a common disorder. Its diagnosis can be made by microscopic examination of voided urine for markers of infection. This manual technique is technically difficult, time-consuming and prone to inter-observer errors. The ...

Dual contrastive learning based image-to-image translation of unstained skin tissue into virtually stained H&E images.

Scientific reports
Staining is a crucial step in histopathology that prepares tissue sections for microscopic examination. Hematoxylin and eosin (H&E) staining, also known as basic or routine staining, is used in 80% of histopathology slides worldwide. To enhance the h...

Content-aware frame interpolation (CAFI): deep learning-based temporal super-resolution for fast bioimaging.

Nature methods
The development of high-resolution microscopes has made it possible to investigate cellular processes in 3D and over time. However, observing fast cellular dynamics remains challenging because of photobleaching and phototoxicity. Here we report the i...