AIMC Topic: Axons

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Efficient, Robust, and Accurate CNN Predictor for Neuronal Activation in Directional Deep Brain Stimulation.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society May 7, 2025
The programming of clinical deep brain stimulation (DBS) systems involves numerous combinations of stimulation parameters, such as stimulus amplitude, pulse width, and frequency. As more complex electrode designs, such as directional electrodes, are ...
Algorithms Computer Simulation Models, Neurological Humans Neural Networks, Computer Axons Finite Element Analysis Neurons Electrodes, Implanted Deep Brain Stimulation
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Deep learning-based segmentation in MRI-(immuno)histological examination of myelin and axonal damage in normal-appearing white matter and white matter hyperintensities.

Brain pathology (Zurich, Switzerland) Aug 23, 2024
The major vascular cause of dementia is cerebral small vessel disease (SVD). Its diagnosis relies on imaging hallmarks, such as white matter hyperintensities (WMH). WMH present a heterogenous pathology, including myelin and axonal loss. Yet, these mi...
Humans Brain Female Male White Matter Middle Aged Magnetic Resonance Imaging Cerebral Small Vessel Diseases Axons Deep Learning Aged Myelin Sheath Aged, 80 and over
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Fine-tuning TrailMap: The utility of transfer learning to improve the performance of deep learning in axon segmentation of light-sheet microscopy images.

PloS one Mar 29, 2024
Light-sheet microscopy has made possible the 3D imaging of both fixed and live biological tissue, with samples as large as the entire mouse brain. However, segmentation and quantification of that data remains a time-consuming manual undertaking. Mach...
Animals Deep Learning Mice Machine Learning Brain Microscopy Axons
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A multi-spectral myelin annotation tool for machine learning based myelin quantification.

F1000Research Nov 15, 2023
Myelin is an essential component of the nervous system and myelin damage causes demyelination diseases. Myelin is a sheet of oligodendrocyte membrane wrapped around the neuronal axon. In the fluorescent images, experts manually identify myelin by co-...
Neural Networks, Computer Myelin Sheath Software Machine Learning Axons
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A Deep Learning Approach for Neuronal Cell Body Segmentation in Neurons Expressing GCaMP Using a Swin Transformer.

eNeuro Sep 26, 2023
Neuronal cell body analysis is crucial for quantifying changes in neuronal sizes under different physiological and pathologic conditions. Neuronal cell body detection and segmentation mainly rely on manual or pseudo-manual annotations. Manual annotat...
Deep Learning Mice Axons Cell Body Neurons Humans Algorithms Animals
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A 5.3 pJ/Spike CMOS Neural Array Employing Time-Modulated Axon-Sharing and Background Mismatch Calibration Techniques.

IEEE transactions on biomedical circuits and systems May 10, 2023
Inspired by the human brain, spiking neuron networks are promising to realize energy-efficient and low-latency neuromorphic computing. However, even state-of-the-art silicon neurons are orders of magnitude worse than biological neurons in terms of ar...
Synapses Calibration Humans Neurons Axons Neural Networks, Computer
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Automated stain-free histomorphometry of peripheral nerve by contrast-enhancing techniques and artificial intelligence.

Journal of neuroscience methods Apr 15, 2022
BACKGROUND: Traditional histopathologic evaluation of peripheral nerve using brightfield microscopy is resource-intensive, necessitating complex sample preparation. Label-free imaging techniques paired with artificial intelligence-based image reconst...
Mammals Coloring Agents Axons Myelin Sheath Animals Mice Artificial Intelligence Sciatic Nerve
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Rapid, automated nerve histomorphometry through open-source artificial intelligence.

Scientific reports Apr 8, 2022
We aimed to develop and validate a deep learning model for automated segmentation and histomorphometry of myelinated peripheral nerve fibers from light microscopic images. A convolutional neural network integrated in the AxonDeepSeg framework was tra...
Artificial Intelligence Nerve Fibers, Myelinated Microscopy Animals Myelin Sheath Rats Axons
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Deep Learning to Decipher the Progression and Morphology of Axonal Degeneration.

Cells Sep 25, 2021
Axonal degeneration (AxD) is a pathological hallmark of many neurodegenerative diseases. Deciphering the morphological patterns of AxD will help to understand the underlying mechanisms and develop effective therapies. Here, we evaluated the progressi...
Nerve Degeneration Animals Neurons Cell Death Disease Models, Animal Deep Learning Humans Axons Neurodegenerative Diseases
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The Flow of Axonal Information Among Hippocampal Subregions: 1. Feed-Forward and Feedback Network Spatial Dynamics Underpinning Emergent Information Processing.

Frontiers in neural circuits Aug 27, 2021
The tri-synaptic pathway in the mammalian hippocampus enables cognitive learning and memory. Despite decades of reports on anatomy and physiology, the functional architecture of the hippocampal network remains poorly understood in terms of the dynami...
Artificial Intelligence Axons Feedback Hippocampus Rats Animals Cognition
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