AIMC Topic: Mitochondrial Precursor Protein Import Complex Proteins

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Classifying Alzheimer's disease and normal subjects using machine learning techniques and genetic-environmental features.

Journal of the Formosan Medical Association = Taiwan yi zhi Dec 2, 2023
BACKGROUND: Alzheimer's disease (AD) is complicated by multiple environmental and polygenetic factors. The accuracy of artificial neural networks (ANNs) incorporating the common factors for identifying AD has not been evaluated.
Humans Neural Networks, Computer Machine Learning Female Aged Aged, 80 and over Sensitivity and Specificity Male Case-Control Studies ROC Curve Polymorphism, Single Nucleotide Support Vector Machine Alzheimer Disease Gene-Environment Interaction Mitochondrial Precursor Protein Import Complex Proteins
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CHCHD4 Oxidoreductase Activity: A Comprehensive Analysis of the Molecular, Functional, and Structural Properties of Its Redox-Regulated Substrates.

Molecules (Basel, Switzerland) May 10, 2025
The human CHCHD4 protein, which is a prototypical family member, carries a coiled-coil-helix-coiled-coil-helix motif that is stabilized by two disulfide bonds. Using its CPC sequence motif, CHCHD4 plays a key role in mitochondrial metabolism, cell su...
Humans Oxidation-Reduction Models, Molecular Mitochondria Substrate Specificity Oxidoreductases Mitochondrial Proteins Mitochondrial Precursor Protein Import Complex Proteins
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