Applied optics
Sep 20, 2022
Recently, polarization-based models for camouflaged object segmentation have attracted research attention. However, to construct this camouflaged object segmentation model, the main challenge is to effectively fuse polarization and light intensity fe...
Briefings in bioinformatics
Sep 20, 2022
Noncoding RNAs (ncRNAs) have recently attracted considerable attention due to their key roles in biology. The ncRNA-proteins interaction (NPI) is often explored to reveal some biological activities that ncRNA may affect, such as biological traits, di...
Briefings in bioinformatics
Sep 20, 2022
An unsolved challenge in developing molecular representation is determining an optimal method to characterize the molecular structure. Comprehension of intramolecular interactions is paramount toward achieving this goal. In this study, ComABAN, a new...
Briefings in bioinformatics
Sep 20, 2022
RNA 5-hydroxymethylcytosine (5hmC) is a kind of RNA modification, which is related to the life activities of many organisms. Studying its distribution is very important to reveal its biological function. Previously, high-throughput sequencing was use...
Briefings in bioinformatics
Sep 20, 2022
Protein S-sulfinylation is an important posttranslational modification that regulates a variety of cell and protein functions. This modification has been linked to signal transduction, redox homeostasis and neuronal transmission in studies. Therefore...
Briefings in bioinformatics
Sep 20, 2022
Drug combination therapies are superior to monotherapy for cancer treatment in many ways. Identifying novel drug combinations by screening is challenging for the wet-lab experiments due to the time-consuming process of the enormous search space of po...
Briefings in bioinformatics
Sep 20, 2022
Many chemicals are present in our environment, and all living species are exposed to them. However, numerous chemicals pose risks, such as developing severe diseases, if they occur at the wrong time in the wrong place. For the majority of the chemica...
Briefings in bioinformatics
Sep 20, 2022
MOTIVATION: Accurate identification of proteins interacted with drugs helps reduce the time and cost of drug development. Most of previous methods focused on integrating multisource data about drugs and proteins for predicting drug-target interaction...
Bioinformatics (Oxford, England)
Sep 16, 2022
MOTIVATION: The tremendous success of graphical neural networks (GNNs) already had a major impact on systems biology research. For example, GNNs are currently being used for drug target recognition in protein-drug interaction networks, as well as for...
Optics letters
Sep 15, 2022
High diffractive efficiency gratings, as a core component in optics, can engineer light transport and separation. This Letter predicts a grating surface with high diffractive efficiency within the visible light wave band with the aid of deep neural n...