AIMC Topic: Pyrones

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Predicting nepetalactone accumulation in Nepeta persica using machine learning algorithms and geospatial analysis.

Scientific reports
Nepeta persica is a medicinal plant with significant pharmacological potential, primarily attributed to its high nepetalactone content. Understanding the environmental drivers of nepetalactone biosynthesis is essential for optimizing both cultivation...

Machine Learning Prediction of Allosteric Drug Activity from Molecular Dynamics.

The journal of physical chemistry letters
Allosteric drugs have been attracting increasing interest over the past few years. In this context, it is common practice to use high-throughput screening for the discovery of non-natural allosteric drugs. While the discovery stage is supported by a ...

Bacillus methylotrophicus ASWU-C2, a strain inhabiting hot desert soil, a new source for antibacterial bacillopyrone, pyrophen, and cyclopeptides.

Zeitschrift fur Naturforschung. C, Journal of biosciences
A strain of Bacillus methylotrophicus was isolated from a soil sample collected in Aswan eastern desert, which is known for its extremely arid climate. After fermentation of the strain in liquid culture and subsequent extraction, a bioassay-guided is...