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Pyruvaldehyde

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The Major Chromophore Arising from Glucose Degradation and Oxidative Stress Occurrence during Lens Proteins Glycation Induced by Glucose.

Molecules (Basel, Switzerland)
Glucose autoxidation has been proposed as a key reaction associated with deleterious effects induced by hyperglycemia in the eye lens. Little is known about chromophores generated during glucose autoxidation. In this study, we analyzed the effect of ...

Protein glycation - biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine.

Redox biology
Protein glycation provides a biomarker in widespread clinical use, glycated hemoglobin HbA (A1C). It is a biomarker for diagnosis of diabetes and prediabetes and of medium-term glycemic control in patients with established diabetes. A1C is an early-s...