AIMC Topic: Glycation End Products, Advanced
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Perspective: Multiomics and Artificial Intelligence for Personalized Nutritional Management of Diabetes in Patients Undergoing Peritoneal Dialysis.
Advances in nutrition (Bethesda, Md.)
Jan 20, 2025
Managing diabetes in patients on peritoneal dialysis (PD) is challenging due to the combined effects of dietary glucose, glucose from dialysate, and other medical complications. Advances in technology that enable continuous biological data collection...
Mulberry leaves ameliorate diabetes via regulating metabolic profiling and AGEs/RAGE and p38 MAPK/NF-κB pathway.
Journal of ethnopharmacology
Oct 6, 2021
ETHNOPHARMACOLOGICAL RELEVANCE: Mulberry leaves have been used as traditional hypoglycemic medicine-food plant for thousand years in China. According to traditional Chinese medicine theory, type 2 diabetes mellitus (T2DM) belongs to the category of X...
3T3-L1 Cells
Glycation End Products, Advanced
Receptor for Advanced Glycation End Products
Plant Leaves
Flavonoids
Diabetes Mellitus, Experimental
NF-kappa B
p38 Mitogen-Activated Protein Kinases
Polysaccharides
Morus
Alkaloids
Mice
Plant Extracts
Hypoglycemic Agents
Hep G2 Cells
Animals
Male
Diabetes Mellitus, Type 2
Humans
Protein glycation - biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine.
Redox biology
Feb 26, 2021
Protein glycation provides a biomarker in widespread clinical use, glycated hemoglobin HbA (A1C). It is a biomarker for diagnosis of diabetes and prediabetes and of medium-term glycemic control in patients with established diabetes. A1C is an early-s...
Quantitative analysis of glycated albumin in serum based on ATR-FTIR spectrum combined with SiPLS and SVM.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
May 7, 2018
A rapid quantitative analysis model for determining the glycated albumin (GA) content based on Attenuated total reflectance (ATR)-Fourier transform infrared spectroscopy (FTIR) combining with linear SiPLS and nonlinear SVM has been developed. Firstly...
New insights into the efficiency of thymol synergistic effect with p-cymene in inhibiting advanced glycation end products: A multi-way analysis based on spectroscopic and electrochemical methods in combination with molecular docking study.
Journal of pharmaceutical and biomedical analysis
Dec 24, 2017
Protein glycation in the body is one of the main reasons of diabetes complications. The electrochemical studies on the inhibitory mechanism of glycation are rather scarce. Thus, it is important to investigate the role of electrochemistry in the glyca...
Molecular Docking Simulation
Lysine
Protein Binding
Serum Albumin, Bovine
Structure-Activity Relationship
Cymenes
Drug Synergism
Glycation End Products, Advanced
Glycosylation
Electrochemical Techniques
Thymol
Monoterpenes
Spectrophotometry, Ultraviolet
Hypoglycemic Agents
Kinetics
Binding Sites
Arginine
Protein Processing, Post-Translational
Protein Conformation
l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor-α levels in patients with type 2 diabetes: a double-blind placebo-controlled randomized clinical trial.
Nutrition research (New York, N.Y.)
Nov 17, 2017
Considering the pathologic importance of metabolic disturbances, advanced glycation end products (AGEs), and chronic inflammation in diabetes mellitus and ameliorating potentials of l-carnosine in hampering these detritions and because these effects ...
Prediction of CML contents in the Maillard reaction products for casein-monosaccharides model.
Food chemistry
Jul 27, 2017
Response surface methodology (RSM) was applied to predict the processing parameters of the casein-glucose/galactose Maillard reaction (MR) for determining the level of N-(1-carboxymethyl)-l-lysine (CML), one of the typically harmful dietary advanced ...
The inhibition of advanced glycation end-products by five fractions and three main flavonoids from Camellia nitidissima Chi flowers.
Journal of food and drug analysis
Apr 18, 2017
Camellia nitidissima Chi (CNC), belonging to Camellia genus (Theaceae family), is a medicinal and edible plant in China. Among the whole plant, the CNC flowers are especially precious, but the biological activities and the compositions of the CNC flo...
Accelerated Biological Aging in Exfoliation Glaucoma Assessed by Fundus-Derived Predicted Age and Advanced Glycation End Products.
International journal of molecular sciences
May 15, 2025
Glaucoma is an age-related neurodegenerative disease characterized by progressive optic nerve damage. Accelerated biological aging, assessed using predicted age derived from fundus images, may serve as a biomarker for glaucoma progression. This study...
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