AI Medical Compendium Topic

Explore the latest research on artificial intelligence and machine learning in medicine.

Receptor, Metabotropic Glutamate 5

Showing 1 to 3 of 3 articles

Clear Filters

Analysis of Drug Design for a Selection of G Protein-Coupled Neuro- Receptors Using Neural Network Techniques.

Current computer-aided drug design 26463104
A study is presented on how well possible drug-molecules can be predicted with respect to their function and binding to a selection of neuro-receptors by the use of artificial neural networks. The ligands investigated in this study are chosen to be c...
Drug Design Humans Ligands Neural Networks, Computer Protein Binding Receptor, Metabotropic Glutamate 5 Receptor, Serotonin, 5-HT2B Receptors, Opioid, mu
View on PubMed DOI

Profiling prediction of nuclear receptor modulators with multi-task deep learning methods: toward the virtual screening.

Briefings in bioinformatics 35998896
Nuclear receptors (NRs) are ligand-activated transcription factors, which constitute one of the most important targets for drug discovery. Current computational strategies mainly focus on a single target, and the transfer of learned knowledge among N...
B-Cell Activation Factor Receptor Calcitonin Receptor-Like Protein Cytokine Receptor gp130 Deep Learning Histamine H2 Antagonists Ligands Neurokinin-1 Receptor Antagonists Proto-Oncogene Proteins c-met Receptor-Like Protein Tyrosine Phosphatases, Class 2 Receptor, Metabotropic Glutamate 5 Receptors, Artificial Receptors, Aryl Hydrocarbon Receptors, Calcitriol Receptors, Cytoplasmic and Nuclear Receptors, Gastrointestinal Hormone Receptors, Muscarinic Receptors, Polymeric Immunoglobulin
View on PubMed DOI

Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques.

Journal of chemical information and modeling 38423996
The world has witnessed a revolution in therapeutics with the development of biological medicines such as antibodies and antibody fragments, notably nanobodies. These nanobodies possess unique characteristics including high specificity and modulatory...
Animals Deep Learning Epitope Mapping Epitopes Models, Molecular Molecular Dynamics Simulation Protein Conformation Rats Receptor, Metabotropic Glutamate 5 Single-Domain Antibodies
View on PubMed DOI
Popular Topics
Recent Journals