AIMC Topic: Receptors, Muscarinic

Clear Filters Showing 1 to 3 of 3 articles

Profiling prediction of nuclear receptor modulators with multi-task deep learning methods: toward the virtual screening.

Briefings in bioinformatics Sep 20, 2022
Nuclear receptors (NRs) are ligand-activated transcription factors, which constitute one of the most important targets for drug discovery. Current computational strategies mainly focus on a single target, and the transfer of learned knowledge among N...
Deep Learning Receptors, Calcitriol Receptors, Aryl Hydrocarbon Receptors, Muscarinic Ligands Receptors, Cytoplasmic and Nuclear Receptor, Metabotropic Glutamate 5 Receptors, Artificial Proto-Oncogene Proteins c-met B-Cell Activation Factor Receptor Calcitonin Receptor-Like Protein Cytokine Receptor gp130 Histamine H2 Antagonists Neurokinin-1 Receptor Antagonists Receptor-Like Protein Tyrosine Phosphatases, Class 2 Receptors, Gastrointestinal Hormone Receptors, Polymeric Immunoglobulin
View on PubMed DOI

Antihypertensive Activity of Sauromatum guttatum Mediated by Vasorelaxation and Myocardial Depressant Effects.

Arquivos brasileiros de cardiologia Dec 1, 2021
BACKGROUND: Sauromatum guttatum (S. guttatum) is used in the treatment of blood disorders and reportedly has a spasmolytic activity through Ca2+ channel inhibition.
Humans Animals Plant Extracts Rats Hypertension Rats, Sprague-Dawley Blood Pressure Antihypertensive Agents Atropine Derivatives Anti-Arrhythmia Agents Calcium Receptors, Muscarinic Vasodilation Verapamil
View on PubMed DOI

Spasmolytic activity of Aquilariae Lignum Resinatum extract on gastrointestinal motility involves muscarinic receptors, calcium channels and NO release.

Pharmaceutical biology Dec 1, 2018
CONTEXT: Aquilariae Lignum Resinatum (ALR), the dry rhizome of Aquilaria agallocha R. (Thymelaeaeeae), has been widely used to treat emesis, stomachache and gastrointestinal dysfunction.
Animals Mice Plant Extracts Rats, Wistar Rats Nitric Oxide Dose-Response Relationship, Drug Thymelaeaceae Receptors, Muscarinic Random Allocation Calcium Channel Blockers Calcium Channels Gastric Emptying Gastrointestinal Motility Muscarinic Antagonists Organ Culture Techniques Parasympatholytics
View on PubMed DOI
Popular Topics
Recent Journals