MOTIVATION: High-resolution Hi-C data are indispensable for the studies of three-dimensional (3D) genome organization at kilobase level. However, generating high-resolution Hi-C data (e.g. 5 kb) by conducting Hi-C experiments needs millions of mammal...
MOTIVATION: Image augmentation is a frequently used technique in computer vision and has been seeing increased interest since the popularity of deep learning. Its usefulness is becoming more and more recognized due to deep neural networks requiring l...
MOTIVATION: A microRNA (miRNA) is a type of non-coding RNA, which plays important roles in many biological processes. Lots of studies have shown that miRNAs are implicated in human diseases, indicating that miRNAs might be potential biomarkers for va...
MOTIVATION: In a predictive modeling setting, if sufficient details of the system behavior are known, one can build and use a simulation for making predictions. When sufficient system details are not known, one typically turns to machine learning, wh...
Journal of bioinformatics and computational biology
Oct 1, 2019
MicroRNAs are single-stranded noncoding RNAs known to down-regulate target genes at the protein or mRNA level. Computational prediction of targets is essential for elucidating the detailed functions of microRNA. However, prediction specificity and se...
Psychological embeddings provide a powerful formalism for characterizing human-perceived similarity among members of a stimulus set. Obtaining high-quality embeddings can be costly due to algorithm design, software deployment, and participant compens...
NengoDL is a software framework designed to combine the strengths of neuromorphic modelling and deep learning. NengoDL allows users to construct biologically detailed neural models, intermix those models with deep learning elements (such as convoluti...
MOTIVATION: Mirtrons arise from short introns with atypical cleavage by using the splicing mechanism. In the current literature, there is no repository centralizing and organizing the data available to the public. To fill this gap, we developed mirtr...
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