AIMC Topic: SOXE Transcription Factors

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Digital quantification of Ki67 and PRAME in challenging melanocytic lesions - A novel diagnostic tool.

Pathology, research and practice Mar 31, 2025
The interpretation of immunohistochemical markers in melanocytic lesions possesses difficulties due to expression in non-melanocytic cells and the time-consuming, non-reproducible nature of manual assessment. A digital tool that accurately quantifies...
Humans Female Melanoma Skin Neoplasms Adult Biomarkers, Tumor Male Middle Aged Antigens, Neoplasm Immunohistochemistry Ki-67 Antigen SOXE Transcription Factors
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A machine learning algorithm for simulating immunohistochemistry: development of SOX10 virtual IHC and evaluation on primarily melanocytic neoplasms.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Apr 1, 2020
Immunohistochemistry (IHC) is a diagnostic technique used throughout pathology. A machine learning algorithm that could predict individual cell immunophenotype based on hematoxylin and eosin (H&E) staining would save money, time, and reduce tissue co...
Humans Neural Networks, Computer Machine Learning Algorithms Databases, Factual Melanoma Skin Neoplasms Staining and Labeling Immunohistochemistry Melanocytes SOXE Transcription Factors
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