Sediment delivery model (SeDeM) system is innovative tool to correlate micromeritic properties of powders with compressibility. It involves computation of indices which facilitate direct compressibility of solids and enable corrective measures throug...
International journal of pharmaceutics
Apr 27, 2022
The potential of machine vision systems has not currently been exploited for pharmaceutical applications, although expected to provide revolutionary solutions for in-process and final product testing. The presented paper aimed to analyze the particle...
European journal of hospital pharmacy : science and practice
Dec 2, 2021
OBJECTIVES: Liquid medications provide an alternative to splitting pills and dosages by measuring an amount of liquid rather than crushing tablets or opening capsules. Special attention should also be paid to specific patient groups with swallowing d...
PURPOSE: This study aimed to explore the underlying mechanisms of Shenyankangfu tablet (SYKFT) in the treatment of glomerulonephritis (GN) based on network pharmacology, machine learning, molecular docking, and experimental validation.
International journal of pharmaceutics
Oct 6, 2021
This study investigates the usefulness of machine learning for modeling complex relationships in a material library. We tested 81 types of active pharmaceutical ingredients (APIs) and their tablets to construct the library, which included the followi...
International journal of pharmaceutics
Sep 29, 2021
In the manufacturing of pharmaceutical Oral Solid Dosage (OSD) forms, Particle Size Distribution (PSD) and Tensile Strength (TS) are common in-process tests that are controlled in order to achieve the quality targets of the end-product. The Quality b...
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Jul 3, 2021
For oral solid dosage forms, disintegration and dissolution properties are closely related to the powders and particles used in their formulation. However, there remains a strong need to characterize the impact of particle structures on tablet compac...
International journal of pharmaceutics
Jun 30, 2021
Liquisolid systems are emerging formulation approach for poorly soluble drugs, based on adsorption/absorption of drug dispersion and obtaining free-flowing powder with good compressibility. SeDeM Expert System represents a powder processability evalu...
International journal of pharmaceutics
Mar 2, 2021
Capping is the frequently observed mechanical defect in tablets arising from the sub-optimal selection of the formulation composition and their robustness of response toward process parameters. Hence, overcoming capping propensity based on the unders...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Jan 15, 2021
Two chemometric assisted spectrophotometric models were applied for the quantitative analysis of velpatasvir and sofosbuvir in their newly FDA approved pharmaceutical dosage form. The UV absorption spectra of velpatasvir and sofosbuvir showed certain...
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