AIMC Topic: Viloxazine

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Early response to SPN-812 (viloxazine extended-release) can predict efficacy outcome in pediatric subjects with ADHD: a machine learning post-hoc analysis of four randomized clinical trials.

Psychiatry research Jan 5, 2021
Machine learning (ML) was used to determine whether early response can predict efficacy outcome in pediatric subjects with ADHD treated with SPN-812. We used data from four Phase 3 placebo-controlled trials of 100- to 600-mg/day SPN-812 (N=1397; 6-17...
Humans Machine Learning Female Male Adolescent Child Treatment Outcome Body Mass Index Dose-Response Relationship, Drug Randomized Controlled Trials as Topic Double-Blind Method Body Weight Clinical Trials as Topic Drug Administration Schedule Central Nervous System Stimulants Delayed-Action Preparations Attention Deficit Disorder with Hyperactivity Viloxazine
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