AIMC Topic: Viral Tail Proteins

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Identification of the tail assembly chaperone genes of T4-Like phages suggests a mechanism other than translational frameshifting for biogenesis of their encoded proteins.

Virology Nov 18, 2021
Tape measure (TM) proteins are essential for the formation of long-tailed phages. TM protein assembly into tails requires the action of tail assembly chaperones (TACs). TACs (e.g. gpG and gpT of E. coli phage lambda) are usually produced in a short (...
Bacteria Computational Biology Escherichia coli Amino Acid Sequence Genome, Viral Sequence Alignment Sequence Homology, Amino Acid Bacteriophage T4 Conserved Sequence Frameshifting, Ribosomal Molecular Chaperones Viral Tail Proteins Virion Virus Assembly
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Large-scale genomic survey with deep learning-based method reveals strain-level phage specificity determinants.

GigaScience Jan 2, 2024
BACKGROUND: Phage therapy, reemerging as a promising approach to counter antimicrobial-resistant infections, relies on a comprehensive understanding of the specificity of individual phages. Yet the significant diversity within phage populations prese...
Deep Learning Genomics Bacteria Glycoside Hydrolases Genome, Viral Bacteriophages Genome, Bacterial Viral Tail Proteins Host Specificity
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Deep-ABPpred: identifying antibacterial peptides in protein sequences using bidirectional LSTM with word2vec.

Briefings in bioinformatics Sep 2, 2021
The overuse of antibiotics has led to emergence of antimicrobial resistance, and as a result, antibacterial peptides (ABPs) are receiving significant attention as an alternative. Identification of effective ABPs in lab from natural sources is a cost-...
Anti-Bacterial Agents Drug Resistance, Bacterial Peptides Deep Learning Computational Biology Amino Acid Sequence Gram-Negative Bacteria Gram-Positive Bacteria Viral Tail Proteins Streptococcus Phages
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