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Explore the latest research on artificial intelligence and machine learning in medicine.

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Blinded, randomized trial of sonographer versus AI cardiac function assessment.

Nature
Artificial intelligence (AI) has been developed for echocardiography, although it has not yet been tested with blinding and randomization. Here we designed a blinded, randomized non-inferiority clinical trial (ClinicalTrials.gov ID: NCT05140642; no o...

Applications of Artificial Intelligence in the Radiology Roundtrip: Process Streamlining, Workflow Optimization, and Beyond.

Seminars in roentgenology
There are many impactful applications of artificial intelligence (AI) in the electronic radiology roundtrip and the patient's journey through the healthcare system that go beyond diagnostic applications. These tools have the potential to improve qual...

Weakly supervised histopathology image segmentation with self-attention.

Medical image analysis
Accurate segmentation in histopathology images at pixel-level plays a critical role in the digital pathology workflow. The development of weakly supervised methods for histopathology image segmentation liberates pathologists from time-consuming and l...

A deep learning workflow for quantification of micronuclei in DNA damage studies in cultured cancer cell lines: A proof of principle investigation.

Computer methods and programs in biomedicine
The cytokinesis block micronucleus assay is widely used for measuring/scoring/counting micronuclei, a marker of genome instability in cultured and primary cells. Though a gold standard method, this is a laborious and time-consuming process with perso...

Automated quantification of measurable residual disease in chronic lymphocytic leukemia using an artificial intelligence-assisted workflow.

Cytometry. Part B, Clinical cytometry
Detection of measurable residual disease (MRD) in chronic lymphocytic leukemia (CLL) is an important prognostic marker. The most common CLL MRD method in current use is multiparameter flow cytometry, but availability is limited by the need for expert...

Evaluation of auto-segmentation for brachytherapy of postoperative cervical cancer using deep learning-based workflow.

Physics in medicine and biology
. The purpose of this study was to evaluate the accuracy of brachytherapy (BT) planning structures derived from Deep learning (DL) based auto-segmentation compared with standard manual delineation for postoperative cervical cancer.. We introduced a c...

Comparative validation of machine learning algorithms for surgical workflow and skill analysis with the HeiChole benchmark.

Medical image analysis
PURPOSE: Surgical workflow and skill analysis are key technologies for the next generation of cognitive surgical assistance systems. These systems could increase the safety of the operation through context-sensitive warnings and semi-autonomous robot...

APLUS: A Python library for usefulness simulations of machine learning models in healthcare.

Journal of biomedical informatics
Despite the creation of thousands of machine learning (ML) models, the promise of improving patient care with ML remains largely unrealized. Adoption into clinical practice is lagging, in large part due to disconnects between how ML practitioners eva...

Data-Driven and Machine Learning-Based Framework for Image-Guided Single-Cell Mass Spectrometry.

Journal of proteome research
Improved throughput of analysis and lowered limits of detection have allowed single-cell chemical analysis to go beyond the detection of a few molecules in such volume-limited samples, enabling researchers to characterize different functional states ...

Machine Learning-Enabled NIR Spectroscopy. Part 2: Workflow for Selecting a Subset of Samples from Publicly Accessible Data.

AAPS PharmSciTech
An increasingly large dataset of pharmaceutics disciplines is frequently challenging to comprehend. Since machine learning needs high-quality data sets, the open-source dataset can be a place to start. This work presents a systematic method to choose...