Miniaturized lenses with a large depth of field and high imaging quality are desirable for compact optical systems, as they eliminate the need for lens switching and repeated refocusing. Metalenses, composed of flat, subwavelength nanostructures, are... read more
For phase retrieval in a coherent beam combining of 7 fiber amplifiers arranged in a tiled aperture experiment, we demonstrate the feasibility of direct implementation of a light-weight deep-learning model trained on simulated data only. Deep-learnin... read more
Hopfield neural networks, classic examples of associative memories, are well-established models for pattern storage and retrieval. However, the original Hopfield network, characterized by quadratic interactions among neurons, exhibits limited storage... read more
Propagation-based X-ray phase-contrast imaging (PB-XPCI) can produce high-resolution images of soft tissue. However, this usually requires extracting the phase shift from intensity measurement at a single propagation distance through phase retrieval-... read more
Biomedical physics & engineering express
Jan 15, 2026
BACKGROUND: Idiopathic pulmonary fibrosis significantly threatens patient survival and remains a condition with limited effective treatment options. There is an urgent need to expedite the exploration of idiopathic pulmonary fibrosis mechanisms and i... read more
The use of machine learning (ML) is reshaping the design and optimization of nanofiber-based drug delivery systems (N-DDS). Electrospun nanofibers offer high surface area, tunable porosity, and versatile drug encapsulation strategies, making them att... read more
OBJECTIVE: Arrhythmia classification from electrocardiograms (ECGs) suffers from high false positive rates and limited cross-dataset generalization, particularly for atrial fibrillation detection where specificity ranges from 0.72 to 0.98 using conve... read more
Seminars in respiratory and critical care medicine
Jan 15, 2026
Glucocorticoid (GC) therapy has been a cornerstone of critical care; however, its full potential has been constrained by fixed-dose regimens and trial designs that predate current insights into the dynamic, phase-specific functions of glucocorticoid ... read more
BACKGROUND: Objective Structured Clinical Examinations (OSCEs) are used as an evaluation method in medical education, but require significant pedagogical expertise and investment, especially in emerging fields like digital health. Large language mode... read more
BACKGROUND: Parkinson disease (PD) presents diagnostic challenges due to its heterogeneous motor and nonmotor manifestations. Traditional machine learning (ML) approaches have been evaluated on structured clinical variables. However, the diagnostic u... read more
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