Liquid biopsies are transforming oncology, enabling earlier diagnosis, dynamic treatment guidance, and personalized precision medicine, yet current approaches focusing mainly on circulating host cell-free DNA (cfDNA) neglect crucial information withi... read more
Angewandte Chemie (International ed. in English)
Dec 10, 2025
Atropisomers play a vital role in asymmetric synthesis, drug discovery, and the development of functional materials. However, the rational design of atropisomers is challenging due to the difficulty in predicting their configurational stability, whic... read more
This study aimed to evaluate the diagnostic accuracy of multimodal large language models in classifying superior labial frenulum attachments from intraoral photographs using expert consensus as the reference standard. Five experts (two periodontists ... read more
Dolphin communication scientists have led the philosophical vanguard of animal translation research since John C. Lilly popularized the idea of human-dolphin communication in the 1960s, and that tradition continues today as multiple teams pursue brea... read more
PURPOSE: To establish a comparability-first cine-MRI paradigm for small intestinal motility using a unified, feature-agnostic normalized differential motion index (NDMI). On this foundation, we investigated scan-rescan consistency and sensitivity und... read more
INTRODUCTION: Axial pain is a common complication following expansive unilateral open-door laminoplasty (ELAP); however, traditional statistical methods are unable to effectively predict this complication. This study developed machine learning (ML) m... read more
A microscope is essential in scientific and medical research, enabling the magnification of specimens too small for the naked eye. The conventional method of acquisition of images requires pathologists or technicians to manually focus the microscope ... read more
The Journal of bone and joint surgery. American volume
Dec 10, 2025
BACKGROUND: Anterior cruciate ligament (ACL) injuries may lead to long-term neuromuscular and structural adaptations in thigh muscles. Although quadriceps dysfunction is well reported, chronic changes in other muscle groups, especially in nonoperativ... read more
American journal of veterinary research
Dec 10, 2025
OBJECTIVE: To evaluate the agreement of automation tools with expert evaluators in identifying cases meeting inclusion and exclusion criteria for retrospective veterinary studies. METHODS: The review of medical records took place from December 16, 20... read more
Obesity is a complex, rapidly escalating global health challenge that demands innovation across biology, clinical care, and public health. This review synthesizes evidence on artificial intelligence (AI) revolutionizing obesity research and managemen... read more
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