Identification and analysis of significant genes in nonalcoholic steatohepatitis-hepatocellular carcinoma transformation: Bioinformatics analysis and machine learning approach.
Journal:
Molecular immunology
PMID:
39142007
Abstract
PURPOSE: Nonalcoholic steatohepatitis (NASH) has been an increasingly significant contributor to hepatocellular carcinoma (HCC). Understanding the progression from NASH to HCC is critical to early diagnosis and elucidating the underlying mechanisms.
Authors
Keywords
Carcinoma, Hepatocellular
Cell Line, Tumor
Cell Transformation, Neoplastic
Computational Biology
Disease Progression
Gene Expression Regulation, Neoplastic
Humans
Liver Neoplasms
Machine Learning
Non-alcoholic Fatty Liver Disease
Prognosis
Single-Cell Analysis
Suppressor of Cytokine Signaling Proteins