AIMC Topic: Suppressor of Cytokine Signaling Proteins

Clear Filters Showing 1 to 3 of 3 articles

Identification and analysis of significant genes in nonalcoholic steatohepatitis-hepatocellular carcinoma transformation: Bioinformatics analysis and machine learning approach.

Molecular immunology Aug 13, 2024
PURPOSE: Nonalcoholic steatohepatitis (NASH) has been an increasingly significant contributor to hepatocellular carcinoma (HCC). Understanding the progression from NASH to HCC is critical to early diagnosis and elucidating the underlying mechanisms.
Humans Machine Learning Prognosis Disease Progression Cell Line, Tumor Liver Neoplasms Carcinoma, Hepatocellular Single-Cell Analysis Computational Biology Gene Expression Regulation, Neoplastic Non-alcoholic Fatty Liver Disease Cell Transformation, Neoplastic Suppressor of Cytokine Signaling Proteins
View on PubMed DOI

Identification of Hit Compounds Using Artificial Intelligence for the Management of Allergic Diseases.

International journal of molecular sciences Feb 14, 2024
This study aimed to identify and evaluate drug candidates targeting the kinase inhibitory region of suppressor of cytokine signaling (SOCS) 3 for the treatment of allergic rhinitis (AR). Utilizing an artificial intelligence (AI)-based new drug develo...
Artificial Intelligence Cytokines Animals Mice Disease Models, Animal Mice, Inbred BALB C Immunoglobulin E Rhinitis, Allergic Ovalbumin Nasal Mucosa Suppressor of Cytokine Signaling Proteins
View on PubMed DOI

Dissecting Shared Genetic Architecture of Thoracic Aortic Aneurysm and Aortic Related Traits and Identifying SplA/Ryanodine Receptor Domain and SOCS Box Containing 1 Involved in Smooth Muscle Phenotype Switching and Cell Senescence Through Alternative Splicing.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology Nov 30, 2025
Machine learning was employed to annotate images of the thoracic aorta, resulting in the identification of additional thoracic-related targets. However, genetic evaluation of the associations among thoracic aortic traits and their shared genes is lac...
Humans Phenotype Female Animals Male Genome-Wide Association Study Mice Mice, Inbred C57BL Cellular Senescence Muscle, Smooth, Vascular Aorta, Thoracic Myocytes, Smooth Muscle Aortic Aneurysm, Thoracic Alternative Splicing Suppressor of Cytokine Signaling Proteins
View on PubMed DOI
Popular Topics
Recent Journals