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Suppressor of Cytokine Signaling Proteins

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Identification of Hit Compounds Using Artificial Intelligence for the Management of Allergic Diseases.

International journal of molecular sciences 38396957
This study aimed to identify and evaluate drug candidates targeting the kinase inhibitory region of suppressor of cytokine signaling (SOCS) 3 for the treatment of allergic rhinitis (AR). Utilizing an artificial intelligence (AI)-based new drug develo...
Animals Artificial Intelligence Cytokines Disease Models, Animal Immunoglobulin E Mice Mice, Inbred BALB C Nasal Mucosa Ovalbumin Rhinitis, Allergic Suppressor of Cytokine Signaling Proteins
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Identification and analysis of significant genes in nonalcoholic steatohepatitis-hepatocellular carcinoma transformation: Bioinformatics analysis and machine learning approach.

Molecular immunology 39142007
PURPOSE: Nonalcoholic steatohepatitis (NASH) has been an increasingly significant contributor to hepatocellular carcinoma (HCC). Understanding the progression from NASH to HCC is critical to early diagnosis and elucidating the underlying mechanisms.
Carcinoma, Hepatocellular Cell Line, Tumor Cell Transformation, Neoplastic Computational Biology Disease Progression Gene Expression Regulation, Neoplastic Humans Liver Neoplasms Machine Learning Non-alcoholic Fatty Liver Disease Prognosis Single-Cell Analysis Suppressor of Cytokine Signaling Proteins
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