Radiograph accelerated detection and identification of cancer in the lung (RADICAL): a mixed methods study to assess the clinical effectiveness and acceptability of Qure.ai artificial intelligence software to prioritise chest X-ray (CXR) interpretation.

Journal: BMJ open
PMID:

Abstract

INTRODUCTION: Diagnosing and treating lung cancer in early stages is essential for survival outcomes. The chest X-ray (CXR) remains the primary screening tool to identify lung cancers in the UK; however, there is a shortfall of radiologists, while demand continues to increase. Image analysis by machine-learning software has the potential to support radiology workflows with a focus on immediate triage of suspicious X-rays. The RADICAL study will evaluate Qure.ai's 'qXR' software in reducing reporting time for suspicious X-rays in NHS Greater Glasgow & Clyde.

Authors

  • Sean F Duncan
    Digital Health Validation Lab, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, UK.
  • Alex McConnachie
    Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK.
  • James Blackwood
    The Industrial Centre for Artificial Intelligence Research in Digital Diagnostics (iCAIRD), Dept of eHealth, NHS Greater Glasgow and Clyde, Glasgow, UK.
  • David B Stobo
    Radiology, Queen Elizabeth University Hospital, Glasgow, UK.
  • John D Maclay
    Respiratory Medicine, Glasgow Royal Infirmary, Glasgow, UK.
  • O Wu
    From the Department of Radiology (S.W., S.J.T.M., R.B., M.J.R.J.B., E.C.M., I.D., P.G., H.A., A.G.S., O.W.), Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts ona@nmr.mgh.harvard.edu.
  • Evi Germeni
    Health Economics and Health Technology Assessment (HEHTA), University of Glasgow, Glasgow, UK.
  • Dennis Robert
    Qure.AI, Bangalore, India.
  • Banu Bilgili
    Qure.AI, Mumbai, India.
  • Shamie Kumar
    Qure.AI, Bangalore, India.
  • Mark Hall
    Radiology Department, Queen Elizabeth University Hospital, Glasgow, Scotland.
  • David J Lowe
    Emergency Department, Queen Elizabeth University Hospital, Glasgow, Scotland.