Selenium supplementation has beneficial and detrimental effects on immunity to influenza vaccine in older adults.

Journal: Clinical nutrition (Edinburgh, Scotland)
PMID: 26803169

Abstract

BACKGROUND & AIMS: Mortality resulting from influenza (flu) virus infections occurs primarily in the elderly through declining immunity. Studies in mice have suggested beneficial effects of selenium (Se) supplementation on immunity to flu but similar evidence is lacking in humans. A dietary intervention study was therefore designed to test the effects of Se-supplementation on a variety of parameters of anti-flu immunity in healthy subjects aged 50-64 years.

Authors

  • Kamal Ivory
    Gut Health and Food Safety Programme, Institute of Food Research, Norwich, UK. Electronic address: kamal.ivory@ifr.ac.uk.
  • Elena Prieto
    Gut Health and Food Safety Programme, Institute of Food Research, Norwich, UK. Electronic address: elenaprieto0102@gmail.com.
  • Caroline Spinks
    Food and Health Program, Institute of Food Research, Norwich, UK. Electronic address: caroline.spinks@ifr.ac.uk.
  • Charlotte N Armah
    Food and Health Program, Institute of Food Research, Norwich, UK. Electronic address: charlotte.armah@ifr.ac.uk.
  • Andrew J Goldson
    Gut Health and Food Safety Programme, Institute of Food Research, Norwich, UK. Electronic address: Andrew.Goldson@ifr.ac.uk.
  • Jack R Dainty
    Analytical Science Unit, Institute of Food Research, Norwich, UK.
  • Claudio Nicoletti
    Gut Health and Food Safety Programme, Institute of Food Research, Norwich, UK. Electronic address: claudio.nicoletti@ifr.ac.uk.

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