Identification and validation of tissue-based gene biomarkers for acute intestinal graft-versus-host disease(AIGVHD).

Journal: Frontiers in immunology
Published Date:

Abstract

BACKGROUND: Acute intestinal graft-versus-host disease (AIGVHD) is a common complication of allogeneic hematopoietic stem cell transplantation (allo HSCT) with a high mortality rate. The primary aim of the present study is to identify tissue-based gene biomarkers pertinent to AIGVHD, thereby facilitating early diagnosis and exploration of potential therapeutic targets.

Authors

  • Hong Chen
    Department of Nephrology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
  • Liyu Fu
    Graduate School, Guangxi Medical University, Nanning, China.
  • Liying Liu
    Graduate School, Guangxi Medical University, Nanning, China.
  • Yunyan He
    Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.