AIMC Topic: Hematopoietic Stem Cell Transplantation
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Febrile neutropenia management in high-risk neutropenic patients: a narrative review on antibiotic prophylaxis and empirical treatment.
Expert review of anti-infective therapy
Apr 4, 2025
INTRODUCTION: Although febrile neutropenia (FN) remains a major cause of morbidity and mortality in patients with hematologic malignancies and hematopoietic stem cell transplant (HSCT) recipients, the increasing prevalence of antimicrobial resistance...
Pre-transplant and transplant parameters predict long-term survival after hematopoietic cell transplantation using machine learning.
Transplant immunology
Feb 26, 2025
BACKGROUND: Allogeneic hematopoietic stem transplantation (allo-HSCT) constitutes a curative treatment for various hematological malignancies. However, various complications limit the therapeutic efficacy of this approach, increasing the morbidity an...
Raising awareness may increase the likelihood of hematopoietic stem cell donation: a nationwide survey using artificial intelligence.
International journal of hematology
Dec 12, 2024
BACKGROUND: In Italy, the demand for allogeneic transplantation exceeds the number of compatible donors in the Italian Bone Marrow Donor Registry (IBMDR). This study aimed to explore the knowledge, beliefs, opinions, values, and feelings of the Itali...
Differential impact of CD34+ cell dose for different age groups in allogeneic hematopoietic cell transplantation for acute leukemia: a machine learning-based discovery.
Experimental hematology
Nov 23, 2024
Allogeneic hematopoietic cell transplantation (allo-HCT) presents a potentially curative treatment for hematologic malignancies yet carries associated risks and complications. Continuous research focuses on predicting outcomes and identifying risk fa...
Predictive modeling of outcomes in acute leukemia patients undergoing allogeneic hematopoietic stem cell transplantation using machine learning techniques.
Leukemia research
Nov 20, 2024
BACKGROUND: Leukemia necessitates continuous research for effective therapeutic techniques. Acute leukemia (AL) patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) focus on key outcomes such as overall survival (OS), re...
Humans
Machine Learning
Prognosis
Retrospective Studies
Female
Aged
Young Adult
Adult
Follow-Up Studies
Graft vs Host Disease
Adolescent
Survival Rate
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Hematopoietic Stem Cell Transplantation
Child, Preschool
Leukemia, Myeloid, Acute
Leukemia
Transplantation, Homologous
Child
Male
Treatment Outcome
Middle Aged
A machine learning-based workflow for predicting transplant outcomes in patients with sickle cell disease.
British journal of haematology
Oct 22, 2024
Allogeneic haematopoietic cell transplantation (HCT) with HLA-matched sibling donor remains the most established curative therapeutic option for patients with sickle cell disease (SCD). However, it is not without risks, highlighting the need for a ri...
Leveraging machine learning for predicting acute graft-versus-host disease grades in allogeneic hematopoietic cell transplantation for T-cell prolymphocytic leukaemia.
BMC medical research methodology
May 11, 2024
Orphan diseases, exemplified by T-cell prolymphocytic leukemia, present inherent challenges due to limited data availability and complexities in effective care. This study delves into harnessing the potential of machine learning to enhance care strat...
Combining serum microRNAs and machine learning algorithms for diagnosing infectious fever after HSCT.
Annals of hematology
May 1, 2024
Infection post-hematopoietic stem cell transplantation (HSCT) is one of the main causes of patient mortality. Fever is the most crucial clinical symptom indicating infection. However, current microbial detection methods are limited. Therefore, timely...
Embracing the age of artificial intelligence: paradigm shifts, opportunities, and challenges in the treatment of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Science China. Life sciences
Feb 27, 2024
Robot therapy aids mental health in patients with hematological malignancy during hematopoietic stem cell transplantation in a protective isolation unit.
Scientific reports
Feb 27, 2024
Patients with hematological malignancy experience physical and psychological pain, such as a sense of isolation and confinement due to intensive chemotherapy in a protective isolation unit (PIU). We examined whether the intervention of a robotic pupp...
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