Gender-specific sarcopenia screening in hemodialysis: insights from lower limb strength and physiological indicators.

Journal: BMC nephrology
Published Date: May 19, 2025

Abstract

OBJECTIVE: Maintenance hemodialysis (MHD) patients often suffer from sarcopenia, affecting lower limb muscle strength and increasing the risk of falls and mortality. This study aims to develop an auxiliary screening model for sarcopenia in MHD patients based on machine learning methods, utilizing lower limb muscle strength indicators, while paying attention to the gender difference and exploring its value in sarcopenia screening.

Authors

  • Yujie Yang
    College of Computer Science, Sichuan University, Section 1, Southern 1st Ring Rd, Chengdu, Sichuan 610065, P. R. China.
  • Hualong Liao
    Department of Geriatrics and National Clinical Research Center for Geriatrics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Yang Chen
    Orthopedics Department of the First Affiliated Hospital of Tsinghua University, Beijing, China.
  • Ying Qiu
    Department of Endocrinology, The Affiliated Hospital of Yunnan University, Kunming, China.
  • Fei Yan
    Department of Infectious Diseases, Affiliated Taizhou Hospital of Wenzhou Medical University, No.50 Ximeng Road, Taizhou, 317000, China.
  • Ping Fu
    Department of Automatic Test and Control, Harbin Institute of Technology, Harbin 150080, China.
  • Jirong Yue
    Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Yu Chen
    State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
  • Huaihong Yuan
    Department of Nephrology, Institute of Kidney Diseases, West China Hospital of Sichuan University, Chengdu, 610041, China. yuanhuaihong@wchscu.cn.

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