Radiomics-based analysis of choroid plexus abnormalities in neuromyelitis optica spectrum disorders and multiple sclerosis and their clinical implications.

Journal: Multiple sclerosis and related disorders
Published Date: Apr 22, 2025

Abstract

BACKGROUND: The choroid plexus (CP) is closely linked to inflammation in multiple sclerosis (MS). While the CP volume is enlarged in MS compared with healthy controls (HC), no such changes are observed in neuromyelitis optica spectrum disorder (NMOSD), a disease with similar clinical and imaging features to MS. It remains unclear whether the CP plays a similar role in NMOSD as in MS.

Authors

  • Xiaohua Wang
    Department of Radiology, Peking University Third Hospital, Beijing, China.
  • Xiaolong Wang
    Cardiovascular Department, Shuguang Hospital Affiliated to Shanghai University of TCM Shanghai, China.
  • Yuhui Xu
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
  • Zichun Yan
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Zhuowei Shi
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Yanbing Liu
    School of Management, Northwestern Polytechnical University, Xi'an 710129, Shanxi, China.
  • Xiaojuan Liu
    School of Artificial Intelligence, Chongqing University of Technology, Chongqing 400050, People's Republic of China.
  • Yongmei Li
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

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