AIMC Topic: Choroid Plexus

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Sex-related differences and associated transcriptional signatures in the brain ventricular system and cerebrospinal fluid development in full-term neonates.

Biology of sex differences May 25, 2025
BACKGROUND: The cerebrospinal fluid (CSF) is known to serve as a unique environment for neurodevelopment, with specific proteins secreted by epithelial cells of the choroid plexus (CP) playing crucial roles in cortical development and cell differenti...
Brain Female Humans Transcriptome Magnetic Resonance Imaging Cerebrospinal Fluid Infant, Newborn Male Lateral Ventricles Choroid Plexus Sex Characteristics Cerebral Ventricles
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Relevance of choroid plexus volumes in multiple sclerosis.

Fluids and barriers of the CNS May 8, 2025
BACKGROUND: The choroid plexus (ChP) plays a pivotal role in inflammatory processes that occur in multiple sclerosis (MS). The enlargement of the ChP in relapsing-remitting multiple sclerosis (RRMS) is considered to be an indication of disease activi...
Choroid Plexus Magnetic Resonance Imaging Multiple Sclerosis Multiple Sclerosis, Relapsing-Remitting Multiple Sclerosis, Chronic Progressive White Matter Male Middle Aged Adult Cross-Sectional Studies Humans Female
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Radiomics-based analysis of choroid plexus abnormalities in neuromyelitis optica spectrum disorders and multiple sclerosis and their clinical implications.

Multiple sclerosis and related disorders Apr 22, 2025
BACKGROUND: The choroid plexus (CP) is closely linked to inflammation in multiple sclerosis (MS). While the CP volume is enlarged in MS compared with healthy controls (HC), no such changes are observed in neuromyelitis optica spectrum disorder (NMOSD...
Humans Male Machine Learning Middle Aged Female Adult Young Adult Radiomics Retrospective Studies Aquaporin 4 Magnetic Resonance Imaging Neuromyelitis Optica Multiple Sclerosis Choroid Plexus
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High resolution multi-delay arterial spin labeling with self-supervised deep learning denoising for pediatric choroid plexus perfusion MRI.

NeuroImage Jan 30, 2025
Choroid plexus (CP) is an important brain structure that produces cerebrospinal fluid (CSF). CP perfusion has been studied using multi-delay arterial spin labeling (MD-ASL) in adults but not in pediatric populations due to the challenge of small CP s...
Humans Female Deep Learning Adolescent Male Spin Labels Choroid Plexus Perfusion Magnetic Resonance Imaging Child Image Processing, Computer-Assisted Magnetic Resonance Imaging Signal-To-Noise Ratio
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Enhanced choroid plexus segmentation with 3D UX-Net and its association with disease progression in multiple sclerosis.

Multiple sclerosis and related disorders Jun 28, 2024
BACKGROUND: The choroid plexus (CP) is suggested to be closely associated with the neuroinflammation of multiple sclerosis (MS). Segmentation based on deep learning (DL) could facilitate rapid and reproducible volume assessment of the CP, which is cr...
Humans Female Middle Aged Disease Progression Multiple Sclerosis, Relapsing-Remitting Adult Deep Learning Imaging, Three-Dimensional Choroid Plexus Male Magnetic Resonance Imaging
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Deep learning segmentation of the choroid plexus from structural magnetic resonance imaging (MRI): validation and normative ranges across the adult lifespan.

Fluids and barriers of the CNS Feb 29, 2024
BACKGROUND: The choroid plexus functions as the blood-cerebrospinal fluid (CSF) barrier, plays an important role in CSF production and circulation, and has gained increased attention in light of the recent elucidation of CSF circulation dysfunction i...
Longevity Adult Choroid Plexus Aged, 80 and over Middle Aged Image Processing, Computer-Assisted Deep Learning Young Adult Magnetic Resonance Imaging Humans Aged
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