Multi-site, multi-vendor development and validation of a deep learning model for liver stiffness prediction using abdominal biparametric MRI.

Journal: European radiology
Published Date:

Abstract

BACKGROUND: Chronic liver disease (CLD) is a substantial cause of morbidity and mortality worldwide. Liver stiffness, as measured by MR elastography (MRE), is well-accepted as a surrogate marker of liver fibrosis.

Authors

  • Redha Ali
    Imaging Research Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Hailong Li
    College of Energy, Xiamen University, Xiamen, 361005 People's Republic of China.
  • Huixian Zhang
    Imaging Research Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Wen Pan
    State Key Laboratory of Stress Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Scott B Reeder
    From the Departments of Medical Physics (R.Z., X.T., C.Z., D.G., J.W.G., K.L., S.B.R., G.H.C.) and Radiology (M.L.S., J.W.G., K.L., S.B.R., G.H.C.), University of Wisconsin-Madison School of Medicine and Public Health, 1111 Highland Ave, Madison, WI 53705; and Department of Radiology, Henry Ford Health System, Detroit, Mich (Z.Q., N.B.B., T.K.S., J.D.N,).
  • David Harris
    Boston Children's Hospital, Boston, Massachusetts.
  • William Masch
    Department of Radiology, Michigan Medicine, Ann Arbor, MI, USA.
  • Anum Aslam
    Department of Radiology, Michigan Medicine, Ann Arbor, MI, USA.
  • Krishna Shanbhogue
    Department of Radiology, NYU Langone Health, 660 1st Avenue, 3rd Floor, New York, NY, 10016, USA. Krishna.shanbhogue@nyulangone.org.
  • Anas Bernieh
    Division of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Sarangarajan Ranganathan
    Division of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Nehal Parikh
    Neurodevelopmental Disorders Prevention Center, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Jonathan R Dillman
    Department of Radiology, Division of Thoracoabdominal Imaging, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Ave., Cincinnati, OH, 45229-3039, USA. jonathan.dillman@cchmc.org.
  • Lili He
    Department of Food Science, University of Massachusetts Amherst, United States of America. Electronic address: lilihe@foodsci.umass.edu.