Integrative multimodal ultrasound and radiomics for early prediction of neoadjuvant therapy response in breast cancer: a clinical study.

Journal: BMC cancer
Published Date: Jul 9, 2025

Abstract

PURPOSE: This study aimed to develop an early predictive model for neoadjuvant therapy (NAT) response in breast cancer by integrating multimodal ultrasound (conventional B-mode, shear-wave elastography, and contrast-enhanced ultrasound) and radiomics with clinical-pathological data, and to evaluate its predictive accuracy after two cycles of NAT.

Authors

  • Siyu Wang
    School of Nursing, Chengdu University of Traditional Chinese Medicine, Sichuan, Chengdu, 610075, China. Electronic address: 919008390@qq.com.
  • Jingyan Liu
    Department of Ultrasound and West China Biomedical Big Data Center, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, 610000, China.
  • Linlin Song
    Department of Medical Ultrasound, West China Hospital, Sichuan University, Wai nan guo xue xiang 37, Chengdu, 610041, China.
  • Haina Zhao
    Department of Ultrasound and West China Biomedical Big Data Center, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, 610000, China.
  • Xue Wan
    Department of Medical Ultrasound, West China Hospital, Sichuan University, Wai nan guo xue xiang 37, Chengdu, 610041, China.
  • Yulan Peng
    Department of Ultrasound, West China Hospital of Sichuan University, Chengdu, China.

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