A deep learning model for preoperative risk stratification of pancreatic ductal adenocarcinoma based on genomic predictors of liver metastasis.

Journal: European journal of cancer (Oxford, England : 1990)
Published Date: Jul 5, 2025

Abstract

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) frequently presents with occult metastatic disease which can undermine the benefit of local treatment. Improved preoperative tools may enhance risk stratification.

Authors

  • Shuhua Zheng
    Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. shuhua.zheng@northwestern.edu.
  • Yirong Liu
    School of Information Science and Technology, University of Science and Technology of China, Hefei, China. yrliu@ustc.edu.cn.
  • P Troy Teo
    Department of Radiation Oncology, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60611, USA.
  • Yilin Wu
    Department of Forensic Science, Fujian Police College, Fuzhou, China.
  • Jianzhong Zhang
    Wuxi Institute of Technology, Wuxi, Jiangsu 214121, China.
  • Mohamed E Abazeed
    2111 East 96th St/NE-6, Department of Translational Hematology Oncology Research, Cleveland Clinic, Cleveland, OH, 44195.
  • John P Hayes
    Department of Radiation Oncology, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60611, USA. Electronic address: jphayes@nm.org.

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