Accurate and Efficient Detection of Nasopharyngeal Carcinoma Using Multi-Dimensional Features of Plasma Cell-Free DNA.

Journal: Head & neck
Published Date:

Abstract

BACKGROUND: The incidence of Nasopharyngeal carcinoma (NPC) is rising in recent years, especially in some non-developed parts of the world. Hence, cost-efficient means for sensitive detection of NPC are vital.

Authors

  • Song Zhang
    College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
  • Jiahui Tang
    School of Mechanical and Precision Instrument Engineering, Xi'an University of Technology, Xi'an 710048, China.
  • Pin Cui
    Shenzhen Rapha Biotechnology Incorporate, Shenzhen, China.
  • Weihuang He
    Shenzhen Rapha Biotechnology Incorporate, Shenzhen, China.
  • Xiaohui Lin
    School of Computer Science and Technology, Dalian University of Technology, Dalian 116024, China. datas@dlut.edu.cn.
  • Shubing Wang
    Department of Biometrics Research, Merck & Co., Inc., Kenilworth, NJ, USA.
  • Yuanxian Liu
    Department of Otolaryngology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, China.
  • Xiaohua Tan
    Department of Oncology, Shenzhen Third People's Hospital, Shenzhen, China.
  • Shu Xu
    Shenzhen Hospital, University of Chinese Academy of Sciences, Shenzhen, China.
  • Mingji Feng
    Department of Oncology, Shenzhen Key Laboratory of Gastrointestinal Cancer Translational Research, Cancer Institute, Peking University Shenzhen Hospital, Shenzhen-Peking University-Hong Kong University of Science and Technology Medical Center, Shenzhen, China.
  • Hanming Lai
    Department of Oncology, Shenzhen Key Laboratory of Gastrointestinal Cancer Translational Research, Cancer Institute, Peking University Shenzhen Hospital, Shenzhen-Peking University-Hong Kong University of Science and Technology Medical Center, Shenzhen, China.