Targeted bisulfite sequencing identified a panel of DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC).

Journal: Clinical epigenetics
PMID:

Abstract

BACKGROUND: DNA methylation has been implicated as a promising biomarker for precise cancer diagnosis. However, limited DNA methylation-based biomarkers have been described in esophageal squamous cell carcinoma (ESCC).

Authors

  • Weilin Pu
    State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
  • Chenji Wang
    Department of Biochemistry and Molecular Biology, Medical College, Soochow University, Suzhou, Jiangsu China.
  • Sidi Chen
    State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
  • Dunmei Zhao
    Department of Biochemistry and Molecular Biology, Medical College, Soochow University, Suzhou, Jiangsu China.
  • Yinghui Zhou
    Department of Biochemistry and Molecular Biology, Medical College, Soochow University, Suzhou, Jiangsu China.
  • Yanyun Ma
    Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
  • Ying Wang
    Key Laboratory of Macromolecular Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an, Shaanxi 710062, China.
  • Caihua Li
    Genesky Biotechnologies Inc., Shanghai, China.
  • Zebin Huang
    Genesky Biotechnologies Inc., Shanghai, China.
  • Li Jin
    State Key Laboratory of Genetic Engineering and Innovation Center of Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
  • Shicheng Guo
    Center for Human Genetics, Marshfield Clinic Research Foundation, 9500 Gilman Drive, MC0412, Marshfield, Wisconsin 54449 United States.
  • Jiucun Wang
    State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
  • Minghua Wang
    School of Materials and Chemical Engineering, Zhengzhou University of Light Industry, No. 136, Science Avenue, Zhengzhou, 450001, China.