AI-enabled cardiac chambers volumetry in coronary artery calcium scans (AI-CAC) predicts heart failure and outperforms NT-proBNP: The multi-ethnic study of Atherosclerosis.

Journal: Journal of cardiovascular computed tomography
PMID:

Abstract

INTRODUCTION: Coronary artery calcium (CAC) scans contain useful information beyond the Agatston CAC score that is not currently reported. We recently reported that artificial intelligence (AI)-enabled cardiac chambers volumetry in CAC scans (AI-CAC™) predicted incident atrial fibrillation in the Multi-Ethnic Study of Atherosclerosis (MESA). In this study, we investigated the performance of AI-CAC cardiac chambers for prediction of incident heart failure (HF).

Authors

  • Morteza Naghavi
    2 Society for Heart Attack Prevention and Eradication Palo Alto CA.
  • Anthony Reeves
    Department of Computer Engineering, Cornell University, Ithaca, NY, USA.
  • Matthew Budoff
    4 Division of Cardiology Los Angeles Biomedical Research at Harbor-UCLA Medical Center Torrance CA.
  • Dong Li
    Department of Cardiovascular Medicine, Lanzhou University Second Hospital, 730030 Lanzhou, Gansu, China.
  • Kyle Atlas
    HeartLung.AI, Houston, TX, USA.
  • Chenyu Zhang
    Academy of Clinical Medicine, Guizhou Medical University, Guiyang 550004, China.
  • Thomas Atlas
    Tustin Teleradiology, Tustin, CA, USA.
  • Sion K Roy
    The Lundquist Institute, Torrance, CA, USA.
  • Claudia I Henschke
    Department of Radiology, Icahn School of Medicine at Mount Sinai, New York.
  • Nathan D Wong
    Department of Medicine, University of California at Irvine, CA (N.D.W.).
  • Christopher deFilippi
    From the Center for Computational Health, IBM Research, T.J. Watson Research Center, Cambridge, MA (K.N.); Cardiovascular Wellness, Geisinger Health System, Danville, PA (S.R.S.); Digital Medicine, Scripps Health, San Diego, CA (S.R.S.); Cardiology, Inova Heart and Vascular Institute, Fairfax, VA (C.d.); Center for Computational Health, IBM Research, T.J. Watson Research Center, Yorktown Heights, NY (S.D.); and Research, Sutter Health Research, Walnut Creek, CA (W.F.S.).
  • Daniel Levy
    The Framingham Heart Study, Framingham, MA 01701, USA.
  • David F Yankelevitz
    Department of Radiology, Icahn School of Medicine at Mount Sinai, New York.