Evaluation of a Machine-Learning Algorithm for Treatment Planning in Prostate Low-Dose-Rate Brachytherapy.

Journal: International journal of radiation oncology, biology, physics
Published Date: Nov 27, 2016

Abstract

PURPOSE: This work presents the application of a machine learning (ML) algorithm to automatically generate high-quality, prostate low-dose-rate (LDR) brachytherapy treatment plans. The ML algorithm can mimic characteristics of preoperative treatment plans deemed clinically acceptable by brachytherapists. The planning efficiency, dosimetry, and quality (as assessed by experts) of preoperative plans generated with an ML planning approach was retrospectively evaluated in this study.

Authors

  • Alexandru Nicolae
    Department of Physics, Ryerson University, Toronto, Ontario, Canada; Department of Medical Physics, Odette Cancer Center, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
  • Gerard Morton
    Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
  • Hans Chung
    Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
  • Andrew Loblaw
    Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
  • Suneil Jain
    Department of Clinical Oncology, The Northern Ireland Cancer Centre, Belfast City Hospital, Antrim, Northern Ireland, UK.
  • Darren Mitchell
    Department of Clinical Oncology, The Northern Ireland Cancer Centre, Belfast City Hospital, Antrim, Northern Ireland, UK.
  • Lin Lu
    School of Economics and Management, Guangxi Normal University, Guilin, China.
  • Joelle Helou
    Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
  • Motasem Al-Hanaqta
    Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
  • Emily Heath
    Department of Physics, Carleton University, Ottawa, Ontario, Canada.
  • Ananth Ravi
    Department of Medical Physics, Odette Cancer Center, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. Electronic address: ananth.ravi@sunnybrook.ca.

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