Bioprocess and biosystems engineering
Mar 22, 2025
Microbial production of industrially important exopolysaccharide (EPS) from extremophiles has several advantages. In this study, key media components (i.e., sucrose, yeast extract, and urea) were optimized for biomass growth and extracellular EPS pro...
Fast and accurate detection of infectious bacteria in wounds is crucial for effective clinical treatment. However, traditional methods take over 24 h to yield results, which is inadequate for urgent clinical needs. Here, we introduce a deep learning-...
Bioprocess and biosystems engineering
Dec 12, 2023
A continuous stirred tank bioreactor (CSTB) with cell recycling combined with ceramic membrane technology and inoculated with Rhodococcus opacus PD630 was employed to treat petroleum refinery wastewater for simultaneous chemical oxygen demand (COD) r...
Bioprocess and biosystems engineering
Feb 27, 2021
Modern bioprocess development employs statistically optimized design of experiments (DOE) and regression modeling to find optimal bioprocess set points. Using modeling software, such as JMP Pro, it is possible to leverage artificial neural networks (...
Bioprocess and biosystems engineering
Sep 29, 2020
A hybrid neural model (HNM) and particle swarm optimization (PSO) was used to optimize ethanol production by a flocculating yeast, grown on cashew apple juice. HNM was obtained by combining artificial neural network (ANN), which predicted reaction sp...
An accurate and reliable forecast of biosurfactant production with minimum error is useful in any bioprocess engineering. Bacterial isolate FKOD36 capable of producing biosurfactant was isolated in this study and pre-inoculums was prepared from the a...
Bioprocess and biosystems engineering
Apr 16, 2016
The control of bioprocesses can be very challenging due to the fact that these kinds of processes are highly affected by various sources of uncertainty like the intrinsic behavior of the used microorganisms. Due to the reason that these kinds of proc...
Bioprocess and biosystems engineering
Feb 25, 2016
A fuzzy logic feedback control system was developed for process monitoring and feeding control in fed-batch enzymatic hydrolysis of a lignocellulosic biomass, dilute acid-pretreated corn stover. Digested glucose from hydrolysis reaction was assigned ...
Currently, mammalian cells are the most utilized hosts for biopharmaceutical production. The culture media for these cell lines include commonly in their composition a pH indicator. Spectroscopic techniques are used for biopharmaceutical process moni...