AI Medical Compendium Journal:
Human heredity

Showing 1 to 4 of 4 articles

tRNA-DL: A Deep Learning Approach to Improve tRNAscan-SE Prediction Results.

Human heredity
BACKGROUND: tRNAscan-SE is the leading tool for transfer RNA (tRNA) annotation, which has been widely used in the field. However, tRNAscan-SE can return a significant number of false positives when applied to large sequences. Recently, conventional m...

Novel Neural Network Approach to Predict Drug-Target Interactions Based on Drug Side Effects and Genome-Wide Association Studies.

Human heredity
AIMS: We propose a novel machine learning approach to expand the knowledge about drug-target interactions. Our method may help to develop effective, less harmful treatment strategies and to enable the detection of novel indications for existing drugs...

Multivariate Quantitative Multifactor Dimensionality Reduction for Detecting Gene-Gene Interactions.

Human heredity
OBJECTIVES: To determine gene-gene interactions and missing heritability of complex diseases is a challenging topic in genome-wide association studies. The multifactor dimensionality reduction (MDR) method is one of the most commonly used methods for...

Model-Based Multifactor Dimensionality Reduction for Rare Variant Association Analysis.

Human heredity
Genome-wide association studies have revealed a vast amount of common loci associated to human complex diseases. Still, a large proportion of heritability remains unexplained. The extent to which rare genetic variants (RVs) are able to explain a rele...