AI Medical Compendium Journal:
Toxicology in vitro : an international journal published in association with BIBRA

Showing 1 to 4 of 4 articles

MLtox, online phototoxicity prediction webpage.

Toxicology in vitro : an international journal published in association with BIBRA
Phototoxicity, sometimes in the literature referred to as photo-irritation, is a chemically induced reaction requiring light. While it is generally accepted that phototoxicity testing can be performed in the majority of cases in vitro (i.e. without t...

Multi-label classification and label dependence in in silico toxicity prediction.

Toxicology in vitro : an international journal published in association with BIBRA
Most computational predictive models are specifically trained for a single toxicity endpoint and lack the ability to learn dependencies between endpoints, such as those targeting similar biological pathways. In this study, we compare the performance ...

In silico prediction of chemical acute contact toxicity on honey bees via machine learning methods.

Toxicology in vitro : an international journal published in association with BIBRA
In recent years, the decline of honey bees and the collapse of bee colonies have caught the attention of ecologists, and the use of pesticides is one of the main reasons for the decline. Therefore, ecological risk assessment of pesticides is essentia...

A mode-of-action ontology model for safety evaluation of chemicals: Outcome of a series of workshops on repeated dose toxicity.

Toxicology in vitro : an international journal published in association with BIBRA
Repeated dose toxicity evaluation aims at assessing the occurrence of adverse effects following chronic or repeated exposure to chemicals. Non-animal approaches have gained importance in the last decades because of ethical considerations as well as d...