AIMC Topic: Hazardous Substances

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Monitoring of occupational exposure to hazardous medicinal products in robotic compounding.

European journal of hospital pharmacy : science and practice
OBJECTIVE: This study aims to evaluate the risk of occupational exposure to hazardous medicinal products (HMPs) when utilising robotic compounding systems for the preparation of antineoplastic sterile medications. Specifically, it assesses the levels...

Chemical sensors for hazardous substances: advances in design, materials, and applications in environmental monitoring.

Environmental monitoring and assessment
Chemical sensors have become essential tools for real-time detection of hazardous substances in complex environmental systems. This review synthesizes recent advances in sensor technologies, focusing on innovations in materials, architectures, and in...

The potential of decision tree application in threshold analysis of hazardous volatile organic compound release from biochar: Implications for environmental risk assessment.

The Science of the total environment
The release of hazardous volatile organic compounds (HVOCs) from biochar poses a potential threat to both human health and the environment. This study investigates how low pyrolysis temperature (HTT) and the chemical characteristics of lignocellulosi...

Machine Learning-based Classification for the Prioritization of Potentially Hazardous Chemicals with Structural Alerts in Nontarget Screening.

Environmental science & technology
Nontarget screening (NTS) with liquid chromatography high-resolution mass spectrometry (LC-HRMS) is commonly used to detect unknown organic micropollutants in the environment. One of the main challenges in NTS is the prioritization of relevant LC-HRM...

Web server-based deep learning-driven predictive models for respiratory toxicity of environmental chemicals: Mechanistic insights and interpretability.

Journal of hazardous materials
Respiratory toxicity of chemicals is a common clinical and environmental health concern. Currently, most in silico prediction models for chemical respiratory toxicity are often based on a single or vague toxicity endpoint, and machine learning models...

Quantitative prediction of toxicological points of departure using two-stage machine learning models: A new approach methodology (NAM) for chemical risk assessment.

Journal of hazardous materials
Point of departure (POD) is a concept used in risk assessment to calculate the reference dose of exposure that is likely to have no appreciable risk on health. POD can be directly utilized from no observed adverse effect levels (NOAEL) which is the d...

The development of classification-based machine-learning models for the toxicity assessment of chemicals associated with plastic packaging.

Journal of hazardous materials
Assessing chemical toxicity in materials like plastic packaging is critical to safeguarding public health. This study presents the development of classification-based machine learning models to predict the toxicity of chemicals associated with plasti...

Selective Identification of Hazardous Gases Using Flexible, Room-Temperature Operable Sensor Array Based on Reduced Graphene Oxide and Metal Oxide Nanoparticles via Machine Learning.

ACS sensors
Selective detection and monitoring of hazardous gases with similar properties are highly desirable to ensure human safety. The development of flexible and room-temperature (RT) operable chemiresistive gas sensors provides an excellent opportunity to ...

Analysis of production time and capacity for manual and robotic compounding scenarios for parenteral hazardous drugs.

European journal of hospital pharmacy : science and practice
BACKGROUND: The increasing amount of hazardous preparations in combination with shortages leads to a call for more efficient compounding methods. This research aims to evaluate the required amount of time, production capacity and direct labour costs ...

Portable Mass Spectrometry for On-site Detection of Hazardous Volatile Organic Compounds via Robotic Extractive Sampling.

Analytical chemistry
Various hazardous volatile organic compounds (VOCs) are frequently released into environments during accidental events that cause many hazards to ecosystems and humans. Therefore, rapid, sensitive, and on-site detection of hazardous VOCs is crucial t...