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Aldehyde Oxidoreductases

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Detection and Classification of Novel Renal Histologic Phenotypes Using Deep Neural Networks.

The American journal of pathology
With the advent and increased accessibility of deep neural networks (DNNs), complex properties of histologic images can be rigorously and reproducibly quantified. We used DNN-based transfer learning to analyze histologic images of periodic acid-Schif...

Machine learning-guided acyl-ACP reductase engineering for improved in vivo fatty alcohol production.

Nature communications
Alcohol-forming fatty acyl reductases (FARs) catalyze the reduction of thioesters to alcohols and are key enzymes for microbial production of fatty alcohols. Many metabolic engineering strategies utilize FARs to produce fatty alcohols from intracellu...