AIMC Topic: Fatty Alcohols

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Machine learning-guided acyl-ACP reductase engineering for improved in vivo fatty alcohol production.

Nature communications Oct 5, 2021
Alcohol-forming fatty acyl reductases (FARs) catalyze the reduction of thioesters to alcohols and are key enzymes for microbial production of fatty alcohols. Many metabolic engineering strategies utilize FARs to produce fatty alcohols from intracellu...
Metabolic Engineering Aldehyde Oxidoreductases Fatty Alcohols Machine Learning
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Neuroprotective role of 6-Gingerol-rich fraction of Zingiber officinale (Ginger) against acrylonitrile-induced neurotoxicity in male Wistar rats.

Journal of basic and clinical physiology and pharmacology Dec 22, 2018
Background Acrylonitrile (AN) is a neurotoxin that is widely used to manufacture synthetic fibres, plastics and beverage containers. Recently, we reported the ameliorative role of 6-gingerol-rich fraction from Zingiber officinale (Ginger, GRF) on the...
Rats, Wistar Glutathione Transferase Catechols Cerebral Cortex Rats Neuroprotection Glutathione Catalase Lipid Peroxidation Plant Extracts Glutathione Peroxidase Male Zingiber officinale Fatty Alcohols Acrylonitrile Superoxide Dismutase Antioxidants Inflammation Malondialdehyde Interleukin-6 Nitric Oxide Tumor Necrosis Factor-alpha Oxidative Stress Animals
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6-Gingerol inhibits hair cycle via induction of MMP2 and MMP9 expression.

Anais da Academia Brasileira de Ciencias Jan 1, 2017
6-Gingerol is the major active constituent of ginger. In the current study, we aimed to investigate the mechanisms underlying the effects of 6-Gingerol on hair growth. Mice were randomly divided into five groups; after hair depilation (day 0), mice w...
Matrix Metalloproteinase 2 Vascular Endothelial Growth Factor A Matrix Metalloproteinase 9 Fatty Alcohols Enzyme Induction Random Allocation Catechols Animals Female Hair Follicle Fibroblast Growth Factor 7 Mice Plant Extracts Transforming Growth Factor beta Insulin-Like Growth Factor I Male Mice, Inbred C57BL
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[HPLC combined with PCA technology for analysis of five gingerol compounds in different processing degrees of ginger charcoal].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica Nov 1, 2015
To establish a new method for simultaneously determining the content of five gingerol compounds in different processing degrees of ginger charcoal and PCA principal component analysis was conducted for analysis. Samples were analyzed on Ultimate TM X...
Charcoal Zingiber officinale Principal Component Analysis Fatty Alcohols Drugs, Chinese Herbal Chemistry, Pharmaceutical Chromatography, High Pressure Liquid Catechols
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