AIMC Topic: Biological Ontologies

Clear Filters Showing 271 to 280 of 639 articles

Prediction of Human Phenotype Ontology terms by means of hierarchical ensemble methods.

BMC bioinformatics Oct 12, 2017
BACKGROUND: The prediction of human gene-abnormal phenotype associations is a fundamental step toward the discovery of novel genes associated with human disorders, especially when no genes are known to be associated with a specific disease. In this c...
Algorithms Phenotype ROC Curve Humans Biological Ontologies Molecular Sequence Annotation Genetic Association Studies Area Under Curve
View on PubMed DOI

Taxonomy-Based Approaches to Quality Assurance of Ontologies.

Journal of healthcare engineering Oct 11, 2017
Ontologies are important components of health information management systems. As such, the quality of their content is of paramount importance. It has been proven to be practical to develop quality assurance (QA) methodologies based on automated iden...
Biological Ontologies Humans Quality Assurance, Health Care Classification
View on PubMed DOI

A new synonym-substitution method to enrich the human phenotype ontology.

BMC bioinformatics Oct 10, 2017
BACKGROUND: Named entity recognition is critical for biomedical text mining, where it is not unusual to find entities labeled by a wide range of different terms. Nowadays, ontologies are one of the crucial enabling technologies in bioinformatics, pro...
Humans Phenotype Data Mining Biological Ontologies Semantics
View on PubMed DOI

Querying clinical data in HL7 RIM based relational model with morph-RDB.

Journal of biomedical semantics Oct 5, 2017
BACKGROUND: Semantic interoperability is essential when carrying out post-genomic clinical trials where several institutions collaborate, since researchers and developers need to have an integrated view and access to heterogeneous data sources. One p...
Software Algorithms Humans Information Storage and Retrieval Databases, Factual Semantics Internet Biological Ontologies
View on PubMed DOI

Semantic annotation in biomedicine: the current landscape.

Journal of biomedical semantics Sep 22, 2017
The abundance and unstructured nature of biomedical texts, be it clinical or research content, impose significant challenges for the effective and efficient use of information and knowledge stored in such texts. Annotation of biomedical documents wit...
Information Storage and Retrieval Semantics Biological Ontologies Electronic Health Records Biomedical Research Humans
View on PubMed DOI

Investigations on factors influencing HPO-based semantic similarity calculation.

Journal of biomedical semantics Sep 20, 2017
BACKGROUND: Although disease diagnosis has greatly benefited from next generation sequencing technologies, it is still difficult to make the right diagnosis purely based on sequencing technologies for many diseases with complex phenotypes and high ge...
Humans Molecular Sequence Annotation Computational Biology Algorithms Semantics Phenotype Biological Ontologies
View on PubMed DOI

Predicting activities of daily living for cancer patients using an ontology-guided machine learning methodology.

Journal of biomedical semantics Sep 16, 2017
BACKGROUND: Bio-ontologies are becoming increasingly important in knowledge representation and in the machine learning (ML) fields. This paper presents a ML approach that incorporates bio-ontologies and its application to the SEER-MHOS dataset to dis...
Biological Ontologies Data Mining Activities of Daily Living Humans Aged, 80 and over Female Male Machine Learning Aged Middle Aged Neoplasms Retrospective Studies Cohort Studies
View on PubMed DOI

Design of an extensive information representation scheme for clinical narratives.

Journal of biomedical semantics Sep 11, 2017
BACKGROUND: Knowledge representation frameworks are essential to the understanding of complex biomedical processes, and to the analysis of biomedical texts that describe them. Combined with natural language processing (NLP), they have the potential t...
Electronic Health Records Natural Language Processing Data Mining Biological Ontologies Humans
View on PubMed DOI

Ontology-based specification, identification and analysis of perioperative risks.

Journal of biomedical semantics Sep 6, 2017
BACKGROUND: Medical personnel in hospitals often works under great physical and mental strain. In medical decision-making, errors can never be completely ruled out. Several studies have shown that between 50 and 60% of adverse events could have been ...
Risk Assessment Biological Ontologies Humans Software Perioperative Period
View on PubMed DOI

Semantic Modeling for Exposomics with Exploratory Evaluation in Clinical Context.

Journal of healthcare engineering Aug 30, 2017
Exposome is a critical dimension in the precision medicine paradigm. Effective representation of exposomics knowledge is instrumental to melding nongenetic factors into data analytics for clinical research. There is still limited work in (1) modeling...
Iatrogenic Disease Biological Ontologies Unified Medical Language System Environmental Exposure Semantics Humans Pilot Projects
View on PubMed DOI
Popular Topics
Recent Journals