AIMC Topic: Biological Ontologies

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The ontology of medically related social entities: recent developments.

Journal of biomedical semantics
BACKGROUND: The Ontology of Medically Related Social Entities (OMRSE) was initially developed in 2011 to provide a framework for modeling demographic data in Resource Description Framework/Web Ontology Language. It is built upon the Basic Formal Onto...

COMODI: an ontology to characterise differences in versions of computational models in biology.

Journal of biomedical semantics
BACKGROUND: Open model repositories provide ready-to-reuse computational models of biological systems. Models within those repositories evolve over time, leading to different model versions. Taken together, the underlying changes reflect a model's pr...

NeuroRDF: semantic integration of highly curated data to prioritize biomarker candidates in Alzheimer's disease.

Journal of biomedical semantics
BACKGROUND: Neurodegenerative diseases are incurable and debilitating indications with huge social and economic impact, where much is still to be learnt about the underlying molecular events. Mechanistic disease models could offer a knowledge framewo...

The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability.

Journal of biomedical semantics
BACKGROUND: The Cell Ontology (CL) is an OBO Foundry candidate ontology covering the domain of canonical, natural biological cell types. Since its inception in 2005, the CL has undergone multiple rounds of revision and expansion, most notably in its ...

Normalizing acronyms and abbreviations to aid patient understanding of clinical texts: ShARe/CLEF eHealth Challenge 2013, Task 2.

Journal of biomedical semantics
BACKGROUND: The ShARe/CLEF eHealth challenge lab aims to stimulate development of natural language processing and information retrieval technologies to aid patients in understanding their clinical reports. In clinical text, acronyms and abbreviations...

A unified software framework for deriving, visualizing, and exploring abstraction networks for ontologies.

Journal of biomedical informatics
Software tools play a critical role in the development and maintenance of biomedical ontologies. One important task that is difficult without software tools is ontology quality assurance. In previous work, we have introduced different kinds of abstra...

Knowledge Author: facilitating user-driven, domain content development to support clinical information extraction.

Journal of biomedical semantics
BACKGROUND: Clinical Natural Language Processing (NLP) systems require a semantic schema comprised of domain-specific concepts, their lexical variants, and associated modifiers to accurately extract information from clinical texts. An NLP system leve...

Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources.

PLoS computational biology
The diversity of online resources storing biological data in different formats provides a challenge for bioinformaticians to integrate and analyse their biological data. The semantic web provides a standard to facilitate knowledge integration using s...

Large scale biomedical texts classification: a kNN and an ESA-based approaches.

Journal of biomedical semantics
BACKGROUND: With the large and increasing volume of textual data, automated methods for identifying significant topics to classify textual documents have received a growing interest. While many efforts have been made in this direction, it still remai...

An ontology-driven, case-based clinical decision support model for removable partial denture design.

Scientific reports
We present the initial work toward developing a clinical decision support model for specific design of removable partial dentures (RPDs) in dentistry. We developed an ontological paradigm to represent knowledge of a patient's oral conditions and dent...