Studies in health technology and informatics
Jan 1, 2017
BioTop is a domain upper level ontology for the life sciences, based on OWL DL, introduced ten years ago. This paper provides an update of the current state of this resource, with a special focus on BioTop's top level, BioTopLite, which currently con...
Studies in health technology and informatics
Jan 1, 2017
At the heart of the Research Domain Criteria for Mental Disorders is a matrix in which functional aspects of behavior are related to genotypic and (endo-)phenotypic research findings, and the various techniques through which they can been observed. T...
Studies in health technology and informatics
Jan 1, 2017
The biomedical community has now developed a significant number of ontologies. The curation of biomedical ontologies is a complex task as they evolve rapidly, being new versions regularly published. Therefore, methods to support ontology developers i...
Studies in health technology and informatics
Jan 1, 2017
Clinical care and research data are widely dispersed in isolated systems based on heterogeneous data models. Biomedicine predominantly makes use of connected datasets based on the Semantic Web paradigm. Initiatives like Bio2RDF created Resource Descr...
Database : the journal of biological databases and curation
Jan 1, 2017
UNLABELLED: The Immune Epitope Database (IEDB) project incorporates independently developed ontologies and controlled vocabularies into its curation and search interface. This simplifies curation practices, improves the user query experience and faci...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2017
The Protein Ontology (PRO) is the reference ontology for proteins in the Open Biomedical Ontologies (OBO) foundry and consists of three sub-ontologies representing protein classes of homologous genes, proteoforms (e.g., splice isoforms, sequence vari...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2017
As molecular biology has increasingly become a data-intensive discipline, ontologies have emerged as an essential computational tool to assist in the organisation, description and analysis of data. Ontologies describe and classify the entities of int...
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
Mar 13, 2016
Molecular biology is based on two great discoveries: the first is that genes carry hereditary information in the form of linear sequences of nucleotides; the second is that in protein synthesis a sequence of nucleotides is translated into a sequence ...
Studies in health technology and informatics
Jan 1, 2016
We continue our previous work of creating and improving a framework for detecting the differences between hierarchical terminologies and suggesting ways to connect them, which is implemented in an automated tool.